CRE Luciferase Reporter-HEK293 Cell Line

Produktübersicht

• Artikelname: CRE Luciferase Reporter-HEK293 Cell Line
• Artikelnummer: BOB-RC1034
• Hersteller Artikelnummer: RC1034
• Alternativnummer: BOB-RC1034-1VIAL
• Hersteller: Boster Bio
• Kategorie: Zellen/Zellkultur
• Applikation: FA

Produktbeschreibung

The CRE Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the cAMP response element (CRE). The CRE cell line is designed to monitor the cAMP/PKA signaling pathways and can be used for studying GPCR-linked cAMP/PKA signaling pathways as well as screening of agonists, antagonists or signaling inhibitors related with the cAMP/PKA signaling pathways. Functional activity of the cell line has been validated by serum stimulation assay (Figure 1).

Produkteigenschaften

• Puffer: Each vial contains 2 ~ 3 x 10 6 cells in 1 ml of 90% FBS + 10% DMSO.

Anwendungsbeschreibung

• Application Verdünnung: <h2>Application:</h2>Monitor the GPCR-linked cAMP/PKA signaling pathway.Screen for activators or inhibitors of the GPCR-linked cAMP/PKA signaling pathway. <h2>Culture conditions:</h2>Cells should be grown at 37C with 5% CO2 using D

Bilder

Fig-1: Induction of CRE activity by forskolin in CRE HEK293 cells.