Replication Protein A2 (RPA2)(RPA2/3140R), CF647 conjugate, 0.1mg/mL

Produktübersicht

• Artikelname: Replication Protein A2 (RPA2)(RPA2/3140R), CF647 conjugate, 0.1mg/mL
• Artikelnummer: BOT-BNC473140-100
• Hersteller Artikelnummer: BNC473140-100
• Alternativnummer: BOT-BNC473140-100-100UL
• Hersteller: Biotium
• Kategorie: Antikörper
• Applikation: WB
• Konjugation: CF647

Produktbeschreibung

Recognizes a protein of 34 kDa, identified as a subunit of Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB). RPA from human cells is a stable heterotrimer of 70 kDa, 32-34 kDa, and 11-14 kDa subunits (RPA70, RPA32, and RPA14 respectively). It is involved in DNA replication, repair, and recombination. RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase (pol) alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Produkteigenschaften

• Konzentration: 0.1 mg/mL
• Puffer: PBS, 0.1% BSA, 0.05% azide
• Quelle: Animal