Recombinant human TCF4 protein fragment (around aa 365-671) (exact sequence is proprietary)
Konjugation:
CF568
Alternative Synonym:
bHLHb19, Class B basic helix-loop-helix protein 19, Immunoglobulin transcription factor 2, ITF-2, PTHS, SEF2, SL3-3 enhancer factor 2, TCF4, Transcription factor 4
This antibody recognizes a protein of 71 kDa, identified as Transcription Factor 4 (TCF4). It is a basic helix-loop-helix transcription factor. The protein recognizes an Ephrussi-box (E-box) binding site (CANNTG) - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
ELISA: Use Ab at 2-4 ug/mL for coating, Order Ab without BSA, Western blot 1-2 ug/mL, Optimal dilution for a specific application should be determined.|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
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