Human IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) (rIG266), CF568 conjugate, 0.1mg/mL, Clone: [rIG266], Mouse, Monoclonal

Produktübersicht

• Artikelname: Human IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) (rIG266), CF568 conjugate, 0.1mg/mL, Clone: [rIG266], Mouse, Monoclonal
• Artikelnummer: BOT-BNC681789-100
• Hersteller Artikelnummer: BNC681789-100
• Alternativnummer: BOT-BNC681789-100-100UL
• Hersteller: Biotium
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant full-length human IGHG protein
• Konjugation: CF568
• Alternative Synonym: G1m Marker | G2m Marker | G3m Marker | G4m Marker | HDC | Heavy Chain Disease Protein | Human Immunglobulin G | Ig gamma1/2/3/4 Chain C Region | IGHG1 | IGHG2 | IGHG3 | IGHG4 | Immunoglobulin Heavy Constant 1/2/3/4

Produktbeschreibung

Recognizes a protein of 75 kDa, identified as gamma heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: 0.1 mg/mL
• Klon-Bezeichnung: [rIG266]
• Molekulargewicht: 75 kDa
• UniProt: P01857
• Puffer: PBS, 0.1% BSA, 0.05% azide
• Quelle: Animal

Anwendungsbeschreibung

• Anwendungsbeschreibung: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunohistochemistry (formalin-fixed): 0.5-1 ug/mL for 30 min at RT|Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min