AKT1 (Prognostic Marker for Neuroendocrine Tumors)(AKT1/2491), CF568 conjugate, 0.1mg/mL

Produktübersicht

• Artikelname: AKT1 (Prognostic Marker for Neuroendocrine Tumors)(AKT1/2491), CF568 conjugate, 0.1mg/mL
• Artikelnummer: BOT-BNC682491-500
• Hersteller Artikelnummer: BNC682491-500
• Alternativnummer: BOT-BNC682491-500-500UL
• Hersteller: Biotium
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Mouse
• Konjugation: CF568

Produktbeschreibung

AKT1 is a 62 kDa protein and member of the serine/threonine kinase AKT family. AKT1 is also known as Protein Kinase B (PKB) or Rac Protein Kinase Alpha. The Akt family also includes AKT2. Activation of AKT1 by insulin or insulin-growth factor-1 (IGF-1) results in phosphorylation of both Thr 308 and Ser 473. AKT proteins become phosphorylated and activated in insulin/IGF-1-stimulated cells by an upstream kinase(s), and the activation of AKT1 and AKT2 is inhibited by the PI kinase inhibitor wortmannin. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Produkteigenschaften

• Konzentration: 0.1 mg/mL
• Puffer: PBS, 0.1% BSA, 0.05% azide
• Quelle: Animal