TRP1 (Tyrosinase Related Protein 1) (TA99 + TYRP1/807), 0.2mg/mL, Clone: [TA99 TYRP1/807], Mouse, Monoclonal

Produktübersicht

• Artikelname: TRP1 (Tyrosinase Related Protein 1) (TA99 + TYRP1/807), 0.2mg/mL, Clone: [TA99 TYRP1/807], Mouse, Monoclonal
• Artikelnummer: BOT-BNUB0808-100
• Hersteller Artikelnummer: BNUB0808-100
• Alternativnummer: BOT-BNUB0808-100-100UL
• Hersteller: Biotium
• Wirt: Mouse
• Kategorie: Antikörper
• Spezies Reaktivität: Human, Mouse
• Immunogen: SK-MEL-23 cells (TA99), Recombinant full-length human TYRP1 protein (TYRP1/807)
• Alternative Synonym: 5, 6 dihydroxyindole 2 carboxylic acid oxidase, 6-dihydroxyindole-2-carboxylic acid oxidase, Associated with iris pigmentation, CAS2, Catalase B (CATB), DHICA oxidase, Glycoprotein75 (GP75), Melanoma antigen gp75, Tyrosinase-related protein 1 (TYRP1), TYRRP

Produktbeschreibung

This antibody reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: 0.2 mg/mL
• Klon-Bezeichnung: [TA99 TYRP1/807]
• Molekulargewicht: 75 kDa
• UniProt: P17643
• Puffer: PBS, 0.05% BSA, 0.05% azide
• Quelle: Animal

Anwendungsbeschreibung

• Anwendungsbeschreibung: For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Not suitable for FFPE sections|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry