Interferon alpha-1 (IFNA1)(2-48), 0.2mg/mL, Clone: [17564], Mouse, Monoclonal

Artikelnummer: BOT-BNUB0997-500
Artikelname: Interferon alpha-1 (IFNA1)(2-48), 0.2mg/mL, Clone: [17564], Mouse, Monoclonal
Artikelnummer: BOT-BNUB0997-500
Hersteller Artikelnummer: BNUB0997-500
Alternativnummer: BOT-BNUB0997-500-500UL
Hersteller: Biotium
Wirt: Mouse
Kategorie: Antikörper
Spezies Reaktivität: Human
Immunogen: Purified recombinant human IFN-alpha1
Alternative Synonym: IFN alpha, IFN alpha 1/13, IFN alpha 1b, Interferon alpha 13 (IFNA13), Interferon alpha leukocyte (IFL), Interferon alpha-1/13 (IFN-alpha-1/13), Interferon alpha-D (IFN alphaD), Interferon alpha1 (IFNA1), LeIF D
This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
Klonalität: Monoclonal
Konzentration: 0.2 mg/mL
Klon-Bezeichnung: [17564]
Molekulargewicht: 16-27 kDa
UniProt: P01562
Puffer: PBS, 0.05% BSA, 0.05% azide
Quelle: Animal
Anwendungsbeschreibung: For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry