MRP1 / ABCC1 (Multidrug Resistance Related Protein 1) (MRP1/1344), 0.2mg/mL, IgG2a, Clone: [MRP1/1344], Mouse, Monoclonal
Artikelnummer:
BOT-BNUB1344-500
Hersteller Artikelnummer:
BNUB1344-500
Alternativnummer:
BOT-BNUB1344-500-500UL
Hersteller:
Biotium
Wirt:
Mouse
Kategorie:
Antikörper
Spezies Reaktivität:
Human
Immunogen:
Recombinant human full-length ABCC1
Alternative Synonym:
ABC29, ABCC1, ATP binding cassette sub family C (CFTR/MRP) member 1, ATP-binding cassette sub-family C member 1, GSX, Leukotriene C(4) transporter, LTC4 transporter, Multidrug resistance-associated protein 1 (MRP1)
The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry
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