Galectin-1 / Human Placental Lactogen (hPL) (GAL1/1831), 0.2mg/mL

Produktübersicht

• Artikelname: Galectin-1 / Human Placental Lactogen (hPL) (GAL1/1831), 0.2mg/mL
• Artikelnummer: BOT-BNUB1831-100
• Hersteller Artikelnummer: BNUB1831-100
• Alternativnummer: BOT-BNUB1831-100-100UL
• Hersteller: Biotium
• Kategorie: Antikörper
• Applikation: IF, IHC-P, WB

Produktbeschreibung

Galectin-1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14 kD participating in a variety of normal and pathological processes, including cancer progression. Galectin-1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin-1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 molecules present on the surface of lymphocytes. Galectin-1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Produkteigenschaften

• Konzentration: 0.2 mg/mL
• Puffer: PBS, 0.05% BSA, 0.05% azide
• Quelle: Animal