NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), 0.2mg/mL

Produktübersicht

• Artikelname: NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), 0.2mg/mL
• Artikelnummer: BOT-BNUB1836-500
• Hersteller Artikelnummer: BNUB1836-500
• Alternativnummer: BOT-BNUB1836-500-500UL
• Hersteller: Biotium
• Kategorie: Antikörper
• Applikation: IHC-P

Produktbeschreibung

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Produkteigenschaften

• Konzentration: 0.2 mg/mL
• Puffer: PBS, 0.05% BSA, 0.05% azide
• Quelle: Animal