Aldoketomutase, epididymis secretory protein Li 74, Glo1, Glx I, glyoxalase 1 complex, glyoxalase 1 regulatory, glyoxalase 1 structural, glyoxalase domain containing 1, Glyoxalase I, glyoxylase 1, Ketone-aldehyde mutase, lactoyl glutathione lyase, Lactoylglutathione lyase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase
GLO1 is an enzyme involved in the detoxification of methylgyoxal, a byproduct of glycolysis. GLO1 expression has been demonstrated by several studies to be upregulated in various human malignant tumors, including metastatic melanoma and lung carcinoma, and thus is a target for pharmaceutical development. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.