Aldo-keto Reductase Family 1 Member B1 (Adrenal Marker)(CPTC-AKR1B1-2), 0.2mg/mL, Clone: [CPTC-AKR1B1-2], Mouse, Monoclonal
Artikelnummer:
BOT-BNUB2592-100
Hersteller Artikelnummer:
BNUB2592-100
Alternativnummer:
BOT-BNUB2592-100-100UL
Hersteller:
Biotium
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IF, IHC, WB
Spezies Reaktivität:
Human
Immunogen:
Recombinant full-length human AKR1B1 protein
Alternative Synonym:
Aldo-keto reductase family 1 member B1, AKR1B1, Aldehyde Reductase 1, Aldose reductase, Lii5-2 CTCL tumor antigen, low Km aldose reductase
Aldo-keto Reductase Family 1 Member B1 (AKR1B1), also known as aldose reductase or aldehyde reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
