PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)(PMEPA1/2698), 0.2mg/mL, Clone: [PMEPA1/2698], Mouse, Monoclonal

Produktübersicht

• Artikelname: PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)(PMEPA1/2698), 0.2mg/mL, Clone: [PMEPA1/2698], Mouse, Monoclonal
• Artikelnummer: BOT-BNUB2698-500
• Hersteller Artikelnummer: BNUB2698-500
• Alternativnummer: BOT-BNUB2698-500-500UL
• Hersteller: Biotium
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant full-length human PMEPA1 protein
• Alternative Synonym: PMEPA, PMEPA1, Prostate transmembrane protein, androgen induced 1, Solid tumor-associated 1 protein, STAG1, TMEPAI, Transmembrane prostate androgen-induced protein, Transmembrane, prostate androgen induced RNA

Produktbeschreibung

PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: 0.2 mg/mL
• Klon-Bezeichnung: [PMEPA1/2698]
• Molekulargewicht: 32 kDa
• UniProt: Q96W9
• Puffer: PBS, 0.05% BSA, 0.05% azide
• Quelle: Animal