FABP5 (Marker of Metastatic Potential in Colorectal Cancer)(FABP5/3750), 1mg/mL

Produktübersicht

• Artikelname: FABP5 (Marker of Metastatic Potential in Colorectal Cancer)(FABP5/3750), 1mg/mL
• Artikelnummer: BOT-BNUM3750-50
• Hersteller Artikelnummer: BNUM3750-50
• Alternativnummer: BOT-BNUM3750-50-50UL
• Hersteller: Biotium
• Kategorie: Antikörper
• Applikation: IHC-P, WB
• Spezies Reaktivität: Mouse

Produktbeschreibung

This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Produkteigenschaften

• Konzentration: 1 mg/mL
• Puffer: PBS, no BSA, no azide
• Quelle: Animal