GLUT-1 (Tumor Progression and Mesothelioma Marker)(rGLUT1/2476), 1mg/mL

Produktübersicht

• Artikelname: GLUT-1 (Tumor Progression and Mesothelioma Marker)(rGLUT1/2476), 1mg/mL
• Artikelnummer: BOT-BNUM3795-50
• Hersteller Artikelnummer: BNUM3795-50
• Alternativnummer: BOT-BNUM3795-50-50UL
• Hersteller: Biotium
• Kategorie: Antikörper
• Applikation: IHC-P
• Spezies Reaktivität: Mouse

Produktbeschreibung

Recognizes a protein of 55 kDa, which is identified as GLUT-1. Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1 is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung, bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiation of malignant mesothelioma (positive) from reactive mesothelium (negative). Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Produkteigenschaften

• Konzentration: 1 mg/mL
• Puffer: PBS, no BSA, no azide
• Quelle: Animal