Caspase-10 Polyclonal Antibody, PE Conjugated, Rabbit
Artikelnummer:
BSS-BS-0092R-PE
Hersteller Artikelnummer:
bs-0092R-PE
Alternativnummer:
BSS-BS-0092R-PE-100
Hersteller:
Bioss
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
FC, IF
Spezies Reaktivität:
Human
Konjugation:
PE
Alternative Synonym:
MCH4, ALPS2, FLICE2, Caspase-10, CASP-10, Apoptotic protease Mch-4, FAS-associated death domain protein interleukin-1B-converting enzyme 2, ICE-like apoptotic protease 4, CASP10
Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. Isoform C is proteolytically inactive.
