PTPN1 Polyclonal Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: PTPN1 Polyclonal Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BS-0182R-BIOTIN
• Hersteller Artikelnummer: bs-0182R-Biotin
• Alternativnummer: BSS-BS-0182R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Human, Rat
• Konjugation: Biotin
• Alternative Synonym: PTP1B, Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP-1B, PTPN1

Produktbeschreibung

Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK, inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 5770
• UniProt: P18031
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human PTP-1B
• Target-Kategorie: PTPN1

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)