RIP13, Rxrip13, hCIT529I10, hN CoR, hNCoR, KIAA1047, MGC104216, N CoR, N Cor/SMRT corepressor Rip13, N CoR1, NCOR 1, NCoR, NCOR1, Nuclear receptor co repressor 1, Nuclear receptor corepressor 1, Retinoid X receptor interacting protein 13, thyroid hormone and retinoic acid receptor associated corepressor 1, thyroid hormone- and retinoic acid receptor-associated corepressor 1, TRAC 1, TRAC1, Nuclear Receptor Corepressor NCoR, NCOR1_MOUSE.
Nuclear co-repressor 2 (N-CoR2) gene (NCOR2, previously called silencing mediator for retinoid and thyroid hormone receptor SMRT) is recruited to nuclear and non-nuclear receptors in a large repressing complex containing also N-CoR1, mSin3 and HDACs. This large complex represses transcription in absence of ligand. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Tissue specificity: Ubiquitous. It is belongs to the N-CoR nuclear receptor corepressors family.
