Angiopoietin 2 Polyclonal Antibody, PE Conjugated, Rabbit
Artikelnummer:
BSS-BS-0677R-PE
Hersteller Artikelnummer:
bs-0677R-PE
Alternativnummer:
BSS-BS-0677R-PE-100
Hersteller:
Bioss
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, WB
Spezies Reaktivität:
Human
Konjugation:
PE
Alternative Synonym:
ANG2, AGPT2, Angiopoietin-2, ANG-2, ANGPT2
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
