Collagen IV Polyclonal Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: Collagen IV Polyclonal Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BS-0806R-BIOTIN
• Hersteller Artikelnummer: bs-0806R-Biotin
• Alternativnummer: BSS-BS-0806R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Human
• Konjugation: Biotin
• Alternative Synonym: Bru, Raw, Svc, Col4a-1, Del(8)44H, Collagen alpha-1(IV) chain, Col4a1

Produktbeschreibung

Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a chicken-wire meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin (By similarity).

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 12826
• UniProt: P02463
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from mouse Collagen alpha-1(IV) chain
• Target-Kategorie: Collagen IV

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)