AKT1S1 Polyclonal Antibody, AbBy Fluor-405 Conjugated, BF405, Rabbit

Produktübersicht

• Artikelname: AKT1S1 Polyclonal Antibody, AbBy Fluor-405 Conjugated, BF405, Rabbit
• Artikelnummer: BSS-BS-10176R-BF405
• Hersteller Artikelnummer: bs-10176R-BF405
• Alternativnummer: BSS-BS-10176R-BF405-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, WB
• Spezies Reaktivität: Human
• Konjugation: BF405
• Alternative Synonym: AKT1 substrate 1 (proline rich), AKT1 substrate 1, AKT1-S1, AKT1S-1, AKT1S 1, AKT1S1, Lobe, PRAS 40, PRAS-40, PRAS40, Proline rich akt substrate, 40 kDa proline rich AKT substrate, 40 kDa proline-rich AKT substrate, AKT1 S1, AKT1 substrate 1, AKTS1_HUMAN, MGC2865, PRAS40, Proline rich Akt substrate 40 kDa, Proline-rich AKT1 substrate 1.

Produktbeschreibung

Proline Rich Akt Substrate (PRAS40) is a 40 kDa substrate of Akt. Akt and PRAS40 can be found in the phosphoinositide 3 kinase (PI3K) pathway, which plays a role in glucose uptake, cell growth, and apoptosis inhibition. PRAS40 is a 14-3-3 binding protein that reacts with insulin, but whose precise function is not yet known. It may bind SH3 and WW domain containing proteins resulting in a change of function. Activated Akt phosphorylates PRAS40 on threonine 246. Mutation of PRAS40 threonine 246 has been shown to be apoptotic.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 84335
• UniProt: Q96B36
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human PRAS40
• Target-Kategorie: AKT1S1

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)