Phospho-NLK (Thr298) Polyclonal Antibody, PE-Cy5 Conjugated, PE/Cy5, Rabbit

Produktübersicht

• Artikelname: Phospho-NLK (Thr298) Polyclonal Antibody, PE-Cy5 Conjugated, PE/Cy5, Rabbit
• Artikelnummer: BSS-BS-10421R-PE-CY5
• Hersteller Artikelnummer: bs-10421R-PE-Cy5
• Alternativnummer: BSS-BS-10421R-PE-CY5-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human, Mouse
• Konjugation: PE/Cy5
• Alternative Synonym: Nemo-like kinase Thr298, Nemo-like kinase T298, p-Nemo-like kinase Thr298, p-Nemo-like kinase T298, DKFZp761G1211, FLJ21033, LAK1, Nemo like kinase, Nemo-like kinase, Nlk, NLK_HUMAN, Protein LAK1, Serine/threonine protein kinase NLK, Serine/threonine-protein kinase NLK.

Produktbeschreibung

Nemo-like kinase (NLK) plays a role in cell fate determination and is required for differentiation of bone marrow stromal cells. It acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. It may suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. (referenced from swissprot)

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic phosphopeptide derived from human Nemo-like kinase around the phosphorylation site of Thr298
• Target-Kategorie: Phospho-NLK (Thr298)

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000)