CACNA1B (N type) Polyclonal Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: CACNA1B (N type) Polyclonal Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BS-10490R-BIOTIN
• Hersteller Artikelnummer: bs-10490R-Biotin
• Alternativnummer: BSS-BS-10490R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC-Fr, IHC-P
• Spezies Reaktivität: Human
• Konjugation: Biotin
• Alternative Synonym: BIII, CACNN, DYT23, Cav2.2, CACNL1A5, Voltage-dependent N-type calcium channel subunit alpha-1B, Brain calcium channel III, Calcium channel, L type, alpha-1 polypeptide isoform 5, Voltage-gated calcium channel subunit alpha Cav2.2, CACNA1B, CACH5

Produktbeschreibung

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the high-voltage activated (HVA) group and are blocked by omega-conotoxin-GVIA (omega-CTx-GVIA) and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 774
• UniProt: Q00975
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human CACNA1B (N type)
• Target-Kategorie: CACNA1B (N type)

Anwendungsbeschreibung

• Application Verdünnung: ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)