Secretogranin V Polyclonal Antibody, AbBy Fluor-594 Conjugated, BF594, Rabbit
Artikelnummer:
BSS-BS-10762R-BF594
Hersteller Artikelnummer:
bs-10762R-BF594
Alternativnummer:
BSS-BS-10762R-BF594-100
Hersteller:
Bioss
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
FC, IF, WB
Spezies Reaktivität:
Mouse, Rat
Konjugation:
BF594
Alternative Synonym:
7B2, SgV, P7B2, SGNE1, Neuroendocrine protein 7B2, Pituitary polypeptide, Secretogranin V, Secretogranin-5, Secretory granule endocrine protein I, SCG5
Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
