ALDH3A2 Polyclonal Antibody, Cy3 Conjugated, Rabbit

Produktübersicht

• Artikelname: ALDH3A2 Polyclonal Antibody, Cy3 Conjugated, Rabbit
• Artikelnummer: BSS-BS-11797R-CY3
• Hersteller Artikelnummer: bs-11797R-Cy3
• Alternativnummer: BSS-BS-11797R-CY3-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, WB
• Spezies Reaktivität: Human
• Konjugation: Cy3
• Alternative Synonym: Ahd 3, Ahd 3r, Ahd3, Ahd3 r, AL3A2_HUMAN, Aldehyde dehydrogenase 10, Aldehyde dehydrogenase 3, Aldehyde dehydrogenase 3 family, member A2, Aldehyde dehydrogenase family 3 member A2, Aldehyde dehydrogenase family 3, subfamily A2, Aldehyde dehydrogenase, family 3, subfamily A, member 2, ALDH10, Aldh3, ALDH3A2, Aldh4, Aldh4 r, Aldh4r, FALDH, Fatty aldehyde dehydrogenase, FLJ20851, Microsomal aldehyde dehydrogenase, msALDH, SLS.

Produktbeschreibung

Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH3A2 (aldehyde dehydrogenase 3 family, member A2), also known as SLS, FALDH or ALDH10, is a 485 amino acid single-pass membrane protein that localizes to the cytoplasmic side of the endoplasmic reticulum and belongs to the aldehyde dehydrogenase family. Expressed in a variety of tissues, including liver, heart, lung, brain, kidney and placenta, ALDH3A2 catalyzes the NAD+-dependent oxidation of long-chain aliphatic aldehydes to fatty acids, a process that is necessary for detoxification and lipid metabolism. Defects in the gene encoding ALDH3A2 are the cause of Sjoegren-Larsson syndrome (SLS), an autosomal recessive neurocutaneous disorder characterized by severe mental retardation, seizures and speech defects. Multiple isoforms of ALDH3A2 exist due to alternative splicing events.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human ALDH3A2
• Target-Kategorie: ALDH3A2

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)