ITM2C Polyclonal Antibody, PE-Cy7 Conjugated, PE/Cy7, Rabbit

Artikelnummer: BSS-BS-11859R-PE-CY7
Artikelname: ITM2C Polyclonal Antibody, PE-Cy7 Conjugated, PE/Cy7, Rabbit
Artikelnummer: BSS-BS-11859R-PE-CY7
Hersteller Artikelnummer: bs-11859R-PE-Cy7
Alternativnummer: BSS-BS-11859R-PE-CY7-100
Hersteller: Bioss
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Konjugation: PE/Cy7
Alternative Synonym: BRI3, BRICD2C, BRICHOS domain containing 2C, Cerebral protein 14, CT-BRI3, E25, E25C , Integral membrane protein 2C, Integral membrane protein 3, Itm2c, ITM2C_HUMAN, ITM3 antibodyNPD018, Transmembrane protein BRI3.
Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.
Klonalität: Polyclonal
Konzentration: 1ug/ul
NCBI: 81618
UniProt: Q9NQX7
Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Quelle: KLH conjugated synthetic peptide derived from human ITM2C
Target-Kategorie: ITM2C
Application Verdünnung: WB(1:300-5000)