ARFBP1 Polyclonal Antibody, AbBy Fluor-405 Conjugated, BF405, Rabbit

Produktübersicht

• Artikelname: ARFBP1 Polyclonal Antibody, AbBy Fluor-405 Conjugated, BF405, Rabbit
• Artikelnummer: BSS-BS-12512R-BF405
• Hersteller Artikelnummer: bs-12512R-BF405
• Alternativnummer: BSS-BS-12512R-BF405-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF
• Konjugation: BF405
• Alternative Synonym: ARF binding protein 1, ARF BP1, ARF-binding protein 1, ARF-BP1, BJ-HCC-24 tumor antigen, E3 ubiquitin protein ligase HUWE1, E3 ubiquitin-protein ligase HUWE1, HECT, HECT domain protein LASU1, HECT UBA and WWE domain containing protein 1, HectH9, Homologous to E6AP carboxyl terminus homologous protein 9, HUWE, Huwe1, HUWE1_HUMAN, Ib772, KIAA0312, KIAA1578, Large structure of UREB1, LASU1, Mcl 1 ubiquitin ligase E3, Mcl-1 ubiquitin ligase E3, MULE, UBA and WWE domain-containing protein 1, Upstream regulatory element-binding protein 1, URE B1, URE-B1, URE-binding protein 1, UREB 1, UREB1.

Produktbeschreibung

E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Regulates apoptosis by catalyzing the polyubiquitination and degradation of MCL1. Mediates monoubiquitination of DNA polymerase beta (POLB) at Lys-41, Lys-61 and Lys-81, thereby playing a role in base-excision repair. Also ubiquitinates the p53/TP53 tumor suppressor and core histones including H1, H2A, H2B, H3 and H4. Binds to an upstream initiator-like sequence in the preprodynorphin gene. Regulates neural differentiation and proliferation by catalyzing the polyubiquitination and degradation of MYCN. May regulate abundance of CDC6 after DNA damage by polyubiquitinating and targeting CDC6 to degradation.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 382
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human ARF6
• Reinheit: Purified by Protein A.
• Target-Kategorie: ARFBP1

Anwendungsbeschreibung

• Application Verdünnung: IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)