phospho-FMRP (Ser500) Polyclonal Antibody, PE Conjugated, Rabbit

Produktübersicht

• Artikelname: phospho-FMRP (Ser500) Polyclonal Antibody, PE Conjugated, Rabbit
• Artikelnummer: BSS-BS-13188R-PE
• Hersteller Artikelnummer: bs-13188R-PE
• Alternativnummer: BSS-BS-13188R-PE-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: PE
• Alternative Synonym: POF, FMRP, POF1, FRAXA, Fragile X mental retardation protein 1, Protein FMR-1, FMR1

Produktbeschreibung

Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 2332
• UniProt: Q06787
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic phosphopeptide derived from human FMRP around the phosphorylation site of Ser500
• Target-Kategorie: phospho-FMRP (Ser500)

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)