ADRM1 Polyclonal Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: ADRM1 Polyclonal Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BS-13357R-BIOTIN
• Hersteller Artikelnummer: bs-13357R-Biotin
• Alternativnummer: BSS-BS-13357R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC-Fr, IHC-P
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Biotin
• Alternative Synonym: 110 kDa cell membrane glycoprotein, adhesion regulating molecule 1, Adhesion-regulating molecule 1, ADRM 1, Adrm1, ADRM1_HUMAN, ARM 1, ARM-1, ARM1, GP110, hRpn13, Mr 110,000 surface antigen, Proteasomal ubiquitin receptor ADRM1, proteasome regulatory particle non ATPase 13, Proteasome regulatory particle non-ATPase 13, Regulatory particle non ATPase 13, Rpn13, Rpn13 homolog.

Produktbeschreibung

ADRM1 is a 407 amino acid protein that localizes to both the nucleus and the cytoplasm and is thought to be involved in protein recruitment and cell adhesion. An integral membrane protein, ADRM1 functions to recruit UCH-L5, a deubiquitinating enzyme, to the 26S proteasome, and once at the proteasome it promotes the activity of UCH-L5. Additionally, ADRM1 is thought to mediate lymphocyte adhesion in endothelial cells and may thus play a role in lymphocyte homing. ADRM1 expression is induced by IFN-g in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis. Two isoforms of ADRM1 exist due to alternative splicing events.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 11047
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human ADRM1
• Target-Kategorie: ADRM1

Anwendungsbeschreibung

• Application Verdünnung: ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)