GPR44 Polyclonal Antibody, AbBy Fluor-750 Conjugated, BF750, Rabbit

Produktübersicht

• Artikelname: GPR44 Polyclonal Antibody, AbBy Fluor-750 Conjugated, BF750, Rabbit
• Artikelnummer: BSS-BS-13537R-BF750
• Hersteller Artikelnummer: bs-13537R-BF750
• Alternativnummer: BSS-BS-13537R-BF750-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, WB
• Spezies Reaktivität: Human
• Konjugation: BF750
• Alternative Synonym: DP2, DL1R, CD294, CRTH2, GPR44, Prostaglandin D2 receptor 2, Chemoattractant receptor-homologous molecule expressed on Th2 cells, G-protein coupled receptor 44, PTGDR2

Produktbeschreibung

Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 11251
• UniProt: Q9Y5Y4
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human GPR44/CD294
• Target-Kategorie: GPR44

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)