APG4B Polyclonal Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: APG4B Polyclonal Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BS-1384R-BIOTIN
• Hersteller Artikelnummer: bs-1384R-Biotin
• Alternativnummer: BSS-BS-1384R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC-Fr, IHC-P
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Biotin
• Alternative Synonym: APG4B, AUTL1, Cysteine protease ATG4B, AUT-like 1 cysteine endopeptidase, Autophagin-1, Autophagy-related cysteine endopeptidase 1, Autophagy-related protein 4 homolog B, hAPG4B, ATG4B, KIAA0943

Produktbeschreibung

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 23192
• UniProt: Q9Y4P1
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human ATG4B
• Target-Kategorie: APG4B

Anwendungsbeschreibung

• Application Verdünnung: ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)