Phospho-CHEK2 (Thr26) Polyclonal Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: Phospho-CHEK2 (Thr26) Polyclonal Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BS-13909R-BIOTIN
• Hersteller Artikelnummer: bs-13909R-Biotin
• Alternativnummer: BSS-BS-13909R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Konjugation: Biotin
• Alternative Synonym: Chk2 (phospho T26), p-Chk2 (phospho T26), bA444G7, CHK2 checkpoint homolog, CHK2_HUMAN, Serine/threonine-protein kinase Chk2, CDS 1, CDS1, Checkpoint kinase 2, Checkpoint like protein CHK2, Chek 2, Chek2, Chk 2, CHK2 checkpoint homolog (S. pombe), CHK2 checkpoint homolog, HuCds 1, HuCds1, LFS 2, LFS2, PP1425, RAD 53, RAD53, Rad53 homolog, Serine/threonine protein kinase Chk2.

Produktbeschreibung

Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on Ser-216, preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at Thr-18 and Ser-20.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 11200
• UniProt: O96017
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated Synthesised phosphopeptide derived from human CHK2 around the phosphorylation site of Thr26
• Target-Kategorie: Phospho-CHEK2 (Thr26)

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000)