GAI3, 87U6, FLJ26559, G protein alpha inhibiting 3, Gi alpha 3, Gi alpha-3, GNAI3, GNAI3_HUMAN, Guanine nucleotide binding protein G protein alpha inhibiting activity polypeptide 3, Guanine nucleotide binding protein Gk alpha subunit, Guanine nucleotide-
GAI3 is the a subunit of inhibitory trimeric G protein (Gi), which inhibits adenylate cyclase once its G protein coupled receptors (GPCR) such as a2 adrenergic receptors are activated. GAI3 can be inactivated by pertussis toxin. Guanine nucleotide bindin