Exonuclease 3-5 domain-containing protein 2, EXD2, C14orf114, EXDL2
Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3-5 exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
