Piezo-type mechanosensitive ion channel component 1, Piezo-type mechanosensitive ion channel component 2, PIEZO1, PIEZO2, Mib, C18orf30, C18orf58, FAM38B, FAM38A, KIAA0233
Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. Piezo comes from the Greek piesi, meaning pressure. The FAM38A gene encodes PIEZO1, a protein that induces mechanically activated (MA) currents in various cell types. PIEZO2 Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Required for Merkel-cell mechanotransduction. Plays a major role in light-touch mechanosensation