PDCD4 Polyclonal Antibody, Biotin Conjugated, Rabbit

Artikelnummer: BSS-BS-1608R-BIOTIN
Artikelname: PDCD4 Polyclonal Antibody, Biotin Conjugated, Rabbit
Artikelnummer: BSS-BS-1608R-BIOTIN
Hersteller Artikelnummer: bs-1608R-Biotin
Alternativnummer: BSS-BS-1608R-BIOTIN-100
Hersteller: Bioss
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, IHC-Fr, IHC-P, WB
Spezies Reaktivität: Human, Mouse, Rat
Konjugation: Biotin
Alternative Synonym: H731, Programmed cell death protein 4, Neoplastic transformation inhibitor protein, Nuclear antigen H731-like, Protein 197/15a, PDCD4
Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).
Klonalität: Polyclonal
Konzentration: 1ug/ul
NCBI: 27250
UniProt: Q53EL6
Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Quelle: KLH conjugated synthetic peptide derived from human PDCD4
Target-Kategorie: PDCD4
Application Verdünnung: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)