phospho-STAT3 (Tyr705) Polyclonal Antibody, PE-Cy5 Conjugated, PE/Cy5, Rabbit

Produktübersicht

• Artikelname: phospho-STAT3 (Tyr705) Polyclonal Antibody, PE-Cy5 Conjugated, PE/Cy5, Rabbit
• Artikelnummer: BSS-BS-1658R-PE-CY5
• Hersteller Artikelnummer: bs-1658R-PE-Cy5
• Alternativnummer: BSS-BS-1658R-PE-CY5-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, WB
• Spezies Reaktivität: Gallus, Human, Mouse, Rat
• Konjugation: PE/Cy5
• Alternative Synonym: APRF, HIES, ADMIO, Signal transducer and activator of transcription 3, Acute-phase response factor, STAT3

Produktbeschreibung

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 6774
• UniProt: P40763
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic phosphopeptide derived from human STAT3 around the phosphorylation site of Tyr705
• Target-Kategorie: phospho-STAT3 (Tyr705)

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), FCM(1:20-100)