HEF1 (phospho S369), p-HEF1 (phospho S369), Cas like docking, Cas scaffolding protein family member 2, CAS-L, CAS2, CasL, CASL_HUMAN, CASS2, Crk associated substrate related, Crk associated substrate related protein, CRK-associated substrate-related protein, dJ49G10.2 (Enhancer of Filamentation 1 (HEF1)), dJ49G10.2, dJ761I2.1 (enhancer of filamentation (HEF1)), dJ761I2.1, Enhancer of filamentation 1, Enhancer of filamentation 1 p55, HEF 1, HEF1
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
