phospho-GRK2 (Ser670) Polyclonal Antibody, Cy5 Conjugated, Rabbit

Produktübersicht

• Artikelname: phospho-GRK2 (Ser670) Polyclonal Antibody, Cy5 Conjugated, Rabbit
• Artikelnummer: BSS-BS-16682R-CY5
• Hersteller Artikelnummer: bs-16682R-Cy5
• Alternativnummer: BSS-BS-16682R-CY5-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF
• Spezies Reaktivität: Human, Mouse
• Konjugation: Cy5
• Alternative Synonym: GRK2 (phospho S670), p-GRK2 (phospho S670), G-protein coupled receptor kinase 2, ADRBK 1, ADRBK1, Adrenergic beta receptor kinase 1, BARK 1, BARK, BARK1, Beta adrenergic receptor kinase 1, Beta ARK 1, Beta ARK1, G Protein Coupled Receptor Kinase 2, G protein dependent receptor kinase 2, FLJ16718, GRK 2, ARBK1_HUMAN.

Produktbeschreibung

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq].

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 156
• UniProt: P25098
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthesised phosphopeptide derived from human GRK2 around the phosphorylation site of Ser670
• Target-Kategorie: phospho-GRK2 (Ser670)

Anwendungsbeschreibung

• Application Verdünnung: IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)