KLHDC8B Polyclonal Antibody, PE Conjugated, Rabbit
Artikelnummer:
BSS-BS-16762R-PE
Hersteller Artikelnummer:
bs-16762R-PE
Alternativnummer:
BSS-BS-16762R-PE-100
Hersteller:
Bioss
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, WB
Spezies Reaktivität:
Human
Konjugation:
PE
Alternative Synonym:
FLJ11302, FP17659, Kelch domain containing 8B, Kelch domain containing protein 8B, Kelch domain-containing protein 8B, KLD8B_HUMAN, Klhdc8b, MGC35097, MGC94736.
Involved in pinching off the separated nuclei at the cleavage furrow and in cytokinesis (PubMed:20107318). Required for mitotic integrity and maintenance of chromosomal stability. Protects cells against mitotic errors, centrosomal amplification, micronucleus formation and aneuploidy. Plays a key role of midbody function involving abscission of the daughter cells during cytokinesis and appropriate chromosomal and nuclear segregation into the daughter cells (PubMed:22988245, PubMed:23713010).