DNA Ligase IV Polyclonal Antibody, AbBy Fluor-350 Conjugated, BF350, Rabbit

Produktübersicht

• Artikelname: DNA Ligase IV Polyclonal Antibody, AbBy Fluor-350 Conjugated, BF350, Rabbit
• Artikelnummer: BSS-BS-1677R-BF350
• Hersteller Artikelnummer: bs-1677R-BF350
• Alternativnummer: BSS-BS-1677R-BF350-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, WB
• Spezies Reaktivität: Human
• Konjugation: BF350
• Alternative Synonym: LIG4S, DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4, LIG4

Produktbeschreibung

Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 3981
• UniProt: P49917
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human DNA Ligase IV
• Target-Kategorie: DNA Ligase IV

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)