KMT3C Polyclonal Antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: KMT3C Polyclonal Antibody, Unconjugated, Rabbit
• Artikelnummer: BSS-BS-16796R
• Hersteller Artikelnummer: bs-16796R
• Alternativnummer: BSS-BS-16796R-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Unconjugated
• Alternative Synonym: KMT3C, HSKM-B, ZMYND14, N-lysine methyltransferase SMYD2, Histone methyltransferase SMYD2, Lysine N-methyltransferase 3C, SET and MYND domain-containing protein 2, SMYD2

Produktbeschreibung

Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 Lys-4 (H3K4me) and dimethylates histone H3 Lys-36 (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates Lys-370 of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at Lys-860.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 56950
• UniProt: Q9NRG4
• Puffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human SMYD2
• Target-Kategorie: KMT3C

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)