DR5 Polyclonal Antibody, PE-Cy7 Conjugated, PE/Cy7, Rabbit

Produktübersicht

• Artikelname: DR5 Polyclonal Antibody, PE-Cy7 Conjugated, PE/Cy7, Rabbit
• Artikelnummer: BSS-BS-1696R-PE-CY7
• Hersteller Artikelnummer: bs-1696R-PE-Cy7
• Alternativnummer: BSS-BS-1696R-PE-CY7-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Konjugation: PE/Cy7
• Alternative Synonym: MK, DR5, Ly98, KILLER, TRICKB, TRAILR2, TRICK2A, TRICK2B, Tumor necrosis factor receptor superfamily member 10B, Death receptor 5, CD262, Tnfrsf10b

Produktbeschreibung

Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity).

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 21933
• UniProt: Q9QZM4
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from mouse DR5
• Target-Kategorie: DR5

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000)