DUBA, OTU domain-containing protein 5, Deubiquitinating enzyme A, OTUD5
Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards Lys-48- and Lys-63-linked polyubiquitin chains. Can also cleave Lys-11-linked ubiquitin chains (in vitro).