LXR beta Polyclonal Antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: LXR beta Polyclonal Antibody, Unconjugated, Rabbit
• Artikelnummer: BSS-BS-18450R
• Hersteller Artikelnummer: bs-18450R
• Alternativnummer: BSS-BS-18450R-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Mouse
• Konjugation: Unconjugated
• Alternative Synonym: Oxysterols receptor LXR-beta, NR1H2, Liver X receptor beta, Nuclear receptor NER, Nuclear receptor subfamily 1 group H member 2, Ubiquitously-expressed nuclear receptor, NR1H2, LXRB, NER, UNR

Produktbeschreibung

Nuclear receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5-AGGTCA-3 and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8, DLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). Exhibits a ligand-dependent transcriptional activation activity (PubMed:25661920).

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 7376
• UniProt: P55055
• Puffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human LXR beta
• Target-Kategorie: LXR beta

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)