Transition Protein 1 Polyclonal Antibody, Biotin Conjugated, Rabbit
Artikelnummer:
BSS-BS-20307R-BIOTIN
Hersteller Artikelnummer:
bs-20307R-Biotin
Alternativnummer:
BSS-BS-20307R-BIOTIN-100
Hersteller:
Bioss
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ELISA, IHC-Fr, IHC-P, WB
Spezies Reaktivität:
Human
Konjugation:
Biotin
Alternative Synonym:
551G9.2, Anti Eukaryotic Release Factor 3a, Anti G1 to S phase transition 1, Anti GST1, homolog of yeast, eRF 3a, eRF3a, G1 to S phase transition 1, G1 to S phase transition protein 1 homolog, G1 to S phase transition protein, GSPT 1, GSPT1, GST 1, GST1, GTP binding protein GST1 HS, Transition protein 1, ERF3A_MOUSE.
eRF3a is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94% sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohns disease, which is a gastrointestinal inflammatory condition.
