IL-10 Polyclonal Antibody, AbBy Fluor-594 Conjugated, BF594, Rabbit

Produktübersicht

• Artikelname: IL-10 Polyclonal Antibody, AbBy Fluor-594 Conjugated, BF594, Rabbit
• Artikelnummer: BSS-BS-20373R-BF594
• Hersteller Artikelnummer: bs-20373R-BF594
• Alternativnummer: BSS-BS-20373R-BF594-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: BF594
• Alternative Synonym: CSIF, TGIF, GVHDS, IL-10, IL10A, Interleukin-10, Cytokine synthesis inhibitory factor, IL10

Produktbeschreibung

Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. IL-10 Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 3586
• UniProt: P22301
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human IL-10
• Target-Kategorie: IL-10

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), FCM(1:20-100)