GLRB Polyclonal Antibody, Cy5.5 Conjugated, Rabbit

Produktübersicht

• Artikelname: GLRB Polyclonal Antibody, Cy5.5 Conjugated, Rabbit
• Artikelnummer: BSS-BS-20450R-CY5.5
• Hersteller Artikelnummer: bs-20450R-Cy5.5
• Alternativnummer: BSS-BS-20450R-CY5.5-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, WB
• Spezies Reaktivität: Mouse, Rat
• Konjugation: Cy5.5
• Alternative Synonym: Glycine receptor subunit beta, GLRB, Glycine receptor 58 kDa subunit

Produktbeschreibung

Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:8717357, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:25445488, PubMed:11929858, PubMed:23238346). Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1 (PubMed:8717357). Plays an important role in the down-regulation of neuronal excitability (PubMed:11929858, PubMed:23238346). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488).

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 2743
• UniProt: P48167
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human GLRB
• Target-Kategorie: GLRB

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)