Cyclin D1 Polyclonal Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: Cyclin D1 Polyclonal Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BS-20596R-BIOTIN
• Hersteller Artikelnummer: bs-20596R-Biotin
• Alternativnummer: BSS-BS-20596R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Biotin
• Alternative Synonym: Cyclin D1, CyclinD1, Cyclin-D1, B cell ccl/lymphoma 1, B cell leukemia 1, B-cell CLL/lymphoma 1, B-cell leukemia 1, B-cell lymphoma 1 protein, BCL-1, BCL1, BCL1 oncogene, CCND 1, CCND1, CCND1 protein, CCND1/FSTL3 fusion gene, included, CCND1/IGHG1 fusion gene, CCND1/IGHG1 fusion gene, included, CCND1/IGLC1 fusion gene, included, CCND1/PTH fusion gene, included, Parathyroid adenomatosis 1, PRAD1, FSTL3, CCND1_HUMAN, AI327039, B cell lymphoma 1 protein, BCL 1, BCL-1, BCL-1 oncogene, BCL1 oncogene, CCND1/FSTL3 fusion gene, included, cD1, Cyl 1, D11S287E, G1/S specific cyclin D1, G1/S-specific cyclin-D1.,,

Produktbeschreibung

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008].

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 595
• UniProt: P24385
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human Cyclin D1
• Reinheit: Purified by Protein A.
• Target-Kategorie: Cyclin D1
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500)