G protein coupled receptor 49, G-protein coupled receptor 49, G-protein coupled receptor 67, GPCR GPR49, G protein coupled receptor 67, FEX, g protein-coupled receptor fex, G-protein coupled receptor HG38, GPR 49, GPR 67, GPR49, GPR67, Leucine rich repeat containing G protein coupled receptor 5, LGR5, HG 38, HG38, LGR5, LGR5_HUMAN, MGC117008, Leucine-rich repeat-containing G-protein coupled receptor 5, LGR 5, Orphan G protein coupled receptor HG38.,,
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]